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硫链丝菌肽

别名:硫链丝菌素 产品编号:272302 CAS号:1393-48-2 分子式:C72H85N19O18S5 分子量:1664.89

订货信息

订货编号 产品名称 规格 包装 价格 促销折扣 折扣价 数量 操作
A60846-1g 硫链丝菌肽 ≥98% (HPLC) 1g 1994.00 1 1,994.00

化学性质

危险属性

质量标准

属性 密度 1.6400 溶解性 Soluble in DMSO (10 mg/ml), chloroform (10 mg/ml), dioxane, pyridine, glacial acetic acid, and DMF. Insoluble in water 存贮条件 储存温度:-20℃ 描述 产品介绍 Thiostrepton is a cyclic peptide antibiotic, densely packed with thiazoles and other structurally intriguing moieties. Thiostrepton exhibits antibiotic activity through blockade of ribosome turnover after an elongation step in protein synthesis by inhibiting both the dissociation of elongation factor G (EF-G) from the ribosome and the release of inorganic phosphate from EF-G following GTP hydrolysis. Thiostrepton is also described to show efficacy against cancer cell growth through downregulation of the forkhead box M1 (FOXM1) transcription factor, commonly overexpressed in many malignancies. Thiostrepton is an inhibitor of FOXM1 别名 硫链丝菌素;Bryamycin; Thiactin; Alaninamide 生化机理 肽抗生素,阻止延长因子G(EF-G)和GTP结合到50S核糖体亚单元上 应用 A protein synthesis-inhibiting antibiotic
标识符号 GHS07 信号词 Warning 安全声明(欧洲) 22,24/25 危害声明 H302 个人防护设备 Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter RTECS XN6300100 WGK德国 3

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