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西亚试剂:New roles for cell stress sensor

New roles for cell stress sensor

Olive Leavy

Two studies published in Nature Immunology propose new functions for components of the unfolded protein response (UPR) in regulating the homeostasis of CD8α conventional dendritic cells (cDCs) and the survival of plasma cells.

The UPR is a physiological response that helps cells to deal with cellular stress initiated by the accumulation of unfolded proteins in…