西亚试剂：：SNP Detection Technology

SNP detection and scoring methods are many and various. Two recurrent themes are elegant simplicity and advanced technology. An effective method recently developed by the HGBASE team is Dynamic Allele-Specific Hybridization. Currently, most procedures involve target sequence PCR amplification, a burden that limits possibilities for scale-up and automation. This is equally true for the much acclaimed miniature hybridisation array (DNA-chip) concept.Genomic level scoring of cSNPs presents another largely unrecognized hurdle due to the possible existence (usually unknown)of processed pseudogenes.

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