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OCTYL ISOCYANATE
| Flammability | 1 | |
| Toxicity | 3 | |
| Body Contact | 2 | |
| Reactivity | 1 | |
| Chronic | 2 | |
| SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4 | ||
Persons with a history of asthma or other respiratory problems or are known to be
sensitised, should not be engaged in any work involving the handling of isocyanates.
[CCTRADE- Bayer, APMF]. Laboratory reagent; prepolymer. Regeant
C9-H17-NO, CH3(CH2)7NCO
Contact with water liberates toxic gas.
May cause SENSITIZATION by inhalation and skin contact.
Accidental ingestion of the material may be seriously damaging to the health of the individual; animal experiments indicate that ingestion of less than 40 gram may be fatal.
There is some evidence to suggest that this material can causeeye irritation and damage in some persons. Irritation of the eyes may produce a heavy secretion of tears (lachrymation).
The material is not thought to be a skin irritant (as classified using animal models). Temporary discomfort, however, may result from prolonged dermal exposures. Good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting. Skin contact with the material may damage the health of the individual; systemic effects may result following absorption. Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.
Inhalation may produce serious health damage*. Inhalation of aerosols (mists, fumes), generated by the material during the course of normal handling, may produce serious damage to the health of the individual. There is some evidence to suggest that the material can cause respiratory irritation in some persons. The body's response to such irritation can cause further lung damage. The vapor/mist may be highly irritating to the upper respiratory tract and lungs; the response may be severe enough to produce bronchitis and pulmonary edema. Possible neurological symptoms arising from isocyanate exposure include headache, insomnia, euphoria, ataxia, anxiety neurosis, depression and paranoia. Gastrointestinal disturbances are characterized by nausea and vomiting. Pulmonary sensitization may produce asthmatic reactions ranging from minor breathing difficulties to severe allergic attacks; this may occur following a single acute exposure or may develop without warning for several hours after exposure. Sensitized people can react to very low doses, and should not be allowed to work in situations allowing exposure to this material. Continued exposure of sensitized persons may lead to possible long term respiratory impairment.Inhalation hazard is increased at higher temperatures.
Inhaling this product is more likely to cause a sensitization reaction in some persons compared to the general population. Skin contact with the material is more likely to cause a sensitization reaction in some persons compared to the general population. Based on experience with animal studies, there is a possibility that exposure to the material may result in toxic effects to the development of the fetus, at levels which do not cause significant toxic effects to the mother. Persons with a history of asthma or other respiratory problems or are known to be sensitised, should not be engaged in any work involving the handling of isocyanates. [CCTRADE-Bayer, APMF]. Respiratory sensitization may result in allergic/asthma like responses; from coughing and minor breathing difficulties to bronchitis with wheezing, gasping. Sensitization may give severe responses to very low levels of exposure, i.e. hypersensitivity. Sensitized persons should not be allowed to work in situations where exposure may occur.
