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LITHIUM DIMETHYLAMIDE
Flammability | 3 | |
Toxicity | 2 | |
Body Contact | 3 | |
Reactivity | 1 | |
Chronic | 2 | |
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4 |
Intermediate.
C2-H6-Li-N, (CH3)2NLi
Contact with water liberates extremely flammable gases.
Spontaneously flammable in air.
Highly flammable.
May cause fire.
Accidental ingestion of the material may be damaging to the health of the individual. Pyrophoric compounds may produce gastrointestinal damage resulting fromlocal generation of heat. Lithium, in large doses, can cause dizziness and weakness. If a low salt diet is in place, kidney damage can result. There may be dehydration, weight loss, skin effects and thyroid disturbances. Central nervous system effects include slurred speech, blurred vision, numbness, inco-ordination and convulsions. Repeated exposure can cause diarrhea, vomiting, tremor, muscle jerks and very brisk reflexes.
If applied to the eyes, this material causes severe eye damage. Pyrophoric compounds may produce thermal burns on contact with the eye.
There is some evidence to suggest that this material can cause inflammation of the skin on contact in some persons. Skin contact is not thought to have harmful health effects, however the material may still produce health damage following entry through wounds, lesions or abrasions. Pyrophoric compounds can produce irritation with a range of severity. Deep burns can occur in severe cases, with shock. Solution of material in moisture on the skin, or perspiration, may markedly increase skin corrosion and accelerate tissue destruction. Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.
There is some evidence to suggest that this material, if inhaled, can irritate the throat and lungs of some persons. Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive concentrations of particulate are inhaled. The material is not thought to produce either adverse health effects or irritation of the respiratory tract following inhalation (as classified using animal models). Nevertheless, adverse effects have been produced following exposure of animals by at least one other route and good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting. Pyrophoric compounds may decompose giving rise to potent irritants of therespiratory tract.
Lithium compounds can affect the nervous system and muscle. This can cause tremor, inco- ordination, spastic jerks and very brisk reflexes. They may cause birth defects and should not be used when pregnancy is suspected. They are effective in treating manic episodes of bipolar disorder. Restricting sodium in the diet increases the risks of taking lithium. Long term exposure to high dust concentrations may cause changes in lung function i.e. pneumoconiosis; caused by particles less than 0.5 micron penetrating and remaining in the lung. Prime symptom is breathlessness; lung shadows show on X-ray. Limited evidence suggests that repeated or long-term occupational exposure may produce cumulative health effects involving organs or biochemical systems.